Mushroom Medicine Update For HPV & Melanoma

Medicinal, magical, mystical. We are taking a deep dive into the latest news and breakthroughs around mushroom medicine today with our resident expert Dr Michael Traub, ND, FABNO. Today, we're shining a light on new studies using Coriolus to treat HPV and melanoma.

Mushrooms are emerging as one of the most exciting natural treatment options in decades. Along with applications in treating cancer and other chronic diseases, physicians and researchers are rediscovering decades old research that reveals the healing power of psilocybin to treat depression, PTSD and even fear of death in the terminally ill.

Today, we're shining a light on new studies using Coriolus to treat HPV and melanoma. In part two, we're going to be talking about psychedelic mushrooms and the emerging science around psilocybin.

Dr Traub is the past president of the American Association of Naturopathic Physicians and has been honored by them as physician of the year. He's practiced in Hawaii since 1985 and is medical director of the Lokahi Health Center. 


Key Take-Aways

 

Coriolus (Turkey Tail) for chemotherapy, radiation and HPV
In 2020, out of nearly 10 million cancer-related deaths worldwide, 70% were in low-and-middle-income countries. These countries do not have the same degree of access to modern anti-cancer drugs as the west. Therefore Coriolus has an important role to play.

Coriolus has long demonstrated safety and effectiveness in fighting cancer, especially when combined with chemotherapy, radiation and immunotherapy.


HPV & the PALOMA Study
PALOMA study was a phase three trial in Spain that was published last year on the efficacy of a Coriolus-based vaginal gel called Papilocare for Women. It normalized the presence of HPV in women who had cervical abnormalities on pap smears. It was a multicenter, open label, randomized parallel group, watchful waiting approach-controlled trial that involved 91 HPV positive women. 

Now, that sounds good on the surface, but there are some problems with this study and its conclusions. First, it is not approved for use in the USA. Secondly, the study combined results of both total clearance and partial clearance. From a therapeutic point of view, partial clearance of HPV is not useful.  

Also, they included atypical glandular cells as an outcome measure, which may be a red flag that the researchers didn't really really know what they were doing.


Careful! Using Coriolus as immune support in the treatment of Melanoma
The use of Coriolus as an immune supportive agent in the treatment of melanoma is not a good idea unless it's combined with another treatment.

Here’s why: Several studies over the last year reveal that  melanin pigment and its content in the melanoma inhibits the melanoma cell response to Coriolus. 

Data shows that the susceptibility to Coriolus induced melanoma cell death is significantly increased after cell depigmentation. 

In other words, the darker the melanoma, the more melanin in the melanoma, the less effective Coriolus treatment becomes , and we don't really want that to be happening.

So if we want to use Coriolus to support immune function in patients with melanoma, it's a good idea to combine that treatment with Thiamidol.

Thiamidol is a new skin-lightening ingredient functioning through tyrosinase inhibition, utilizing the same target as hydroquinone.  As hydroquinone has been drawn into question by the US FDA for its safety, skin care manufacturers have been searching for alternatives.

Thiamidol was found to be the most effective melanin production inhibitor in these studies.  This is important because melanin production has been shown to have potent immunosuppressive properties. 

Beiersdorf introduced Thiamidol this year into the US cosmetic market in their Eucerin line of skin care products.
 


Key Quote  


Coriolis is by far the most widely studied medicinal mushroom. Nearly all of the published literature on this mushroom refers to the name of the mushroom as Coriolus. But the actual name of it is Trametes versicolor , not Coriolis. Of course Turkey Tail is the common name".

Dr Michael Traub ND FABNO

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